Search on: HISTAMINE H2 ANTAGONISTS 
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Descriptor English:   Histamine H2 Antagonists 
Descriptor Spanish:   Antagonistas de los Receptores Histamínicos H2 
Descriptor Portuguese:   Antagonistas dos Receptores Histamínicos H2 
Synonyms English:   Antagonists, Histamine H2
Antihistaminics, H2
Blockaders, H2 Receptor
Blockaders, Histamine H2 Receptor
Blockers, Histamine H2
H2 Antagonists, Histamine
H2 Antihistaminics
H2 Blockers, Histamine
H2 Receptor Blockaders
Histamine H2 Blockers
Histamine H2 Receptor Antagonists
Histamine H2 Receptor Blockaders
Receptor Antagonists, Histamine H2
Receptor Blockaders, H2  
Tree Number:   D27.505.519.625.375.425.425
D27.505.696.577.375.425.425
Definition English:   Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood. 
Indexing Annotation English:   GEN or unspecified; prefer specifics; DF: HISTAMINE H2 ANTAG
See Related English:   Anti-Ulcer Agents
 
History Note English:   95; was HISTAMINE H2 RECEPTOR BLOCKADERS 1977-94 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   6794 
Unique Identifier:   D006635 

Occurrence in VHL:
 

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